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- Category: Archives News
- Etude NANORAD 2 : étude clinique pour patients atteints de cancer et présentant des métastases dans le cerveau
- NH TherAguix announces the release of a new clinical batch for it’s drug AGuIX manufactured by CARBOGEN AMCIS
- NH TherAguix staff member awarded with a Ph.D. prize
- Category: Archives News 2019
- Category: Archives News 2021
- NH TherAguix reporte son projet d’introduction en bourse sur le marché Euronext Growth à Paris
- NH TherAguix announces the enrolment in Boston of the first 2 patients in its clinical trials NANOBRAINMETS and NANOSMART
- NH TherAguix announces the launch of its IPO on the Euronext Growth market in Paris
- NH TherAguix registration document approved by Autorité des Marchés Financiers as part of planned IPO on Euronext Growth Paris
- NH TherAguix and the CHU Grenoble-Alpes announce the publication of the results of the First-In-Human phase 1 clinical trial
- Category: Archives News 2022
- NH TherAguix announces the thesis defense of Dr. Paul Rocchi as the first NHT-funded PhD student
- NH TherAguix announces the arrival of Dr. Olivier de Beaumont as Chief Medical Officer
- NH TherAguix et le Centre de Lutte Contre le Cancer Jean PERRIN de Clermont- Ferrand annoncent le recrutement du premier patient dans l’essai clinique Nano-GBM de phase I/II ciblant le glioblastome
- Category: Archives News 2023
- Category: Archives Publications
- Added Value of Scintillating Element in Cerenkov-Induced Photodynamic Therapy
- A New Generation of Ultrasmall Nanoparticles Inducing Sensitization to Irradiation and Copper Depletion to Overcome Radioresistant and Invasive Cancers
- Multimodal imaging Gd-nanoparticles functioalized with Pittsburgh compound B or a nanobody for amyloid plaques targeting
- Proton MR spectroscopy and diffusion MR imaging to predict tumor response to interstitial photodynamic therapy for glioblastoma
- Ultrasmall AGuIX theranostic nanoparticles for vascular-targeted interstitial photodynamic therapy of glioblastoma
- Magnetic resonance lymphography at 9.4 T using a gadolinium-based nanoparticle in rat: investigations in healthy animals and a hindlimb lymphedema model
- Magnetic nanoparticles applications for amyloidosis study and detection: a review
- Functionalization of theranostic AGuIX® nanoparticles for PET/MRI/optical imaging
- Antibody-targeting of ultra-small nanoparticles enhances imaging sensitivity and enables longitudinal tracking of multiple myeloma
- Gd-nanoparticles functionnalization with specific peptides for β-amyloid plaques targeting
- Chemical and in vitro characterizations of a promising bimodal AGuIX probe able to target apoptotic cells for applications in MRI and optical imaging
- MR imaging, targeting and characterization of pulmonary fibrosis using intra-tracheal administration of gadolinium-based nanoparticles
- Pushing radiation therapy limitations with theranostic nanoparticles
- Multifunctionnal ultrasmall nanoplatforms for vascular-targeted interstitial photodynamic therapy of brain tumors guided by real-time MRI
- Ultrasmall nanoplatforms as calcium-responsive contrast agents for magnetic resonance imaging
- Ultrasmall particles for Gd-MRI and 68Ga-PET dual imaging
- Gadolinium based-nanoparticles for theranostic MRI-Radiosensitization
- Nanoparticules ultrafines en radiothérapie : le cas des AGuIX
- Small rigid platforms functionalization with quaternary ammonium : targeting extracellular matrix of chondrosarcoma
- Long distance energy transfer photosensitizers arising in hybrid nanoparticles leading to fluorescence emission and singlet oxygen luminescence quenching
- Multifunctionnal Peptide-Conjugated Hybrid Silica Nanoparticles for Photodynamic Therapy and MRI
- Real-time monitoring of phototoxicity in nanoparticles-based photodynamic therapy : a model-based approach
- Functionnalization of small rigid platforms with cyclic RGD peptides for targeting tumors overexpressing αvβ3 integrins
- Development of gadolinium based nanoparticles having an affinity towards melanin
- In vivo evidence of the targeting of cartilaginous tissue by pyridinium functionalized nanoparticles
- High Resolution Cellular IRM: Gadolinium and Iron Oxides Nanoparticles for in Depth Dual Cell Imaging of Engineered Tissue Constructs
- Bifunctionnal polypyridyl-Ru(II) complex grafted onto gadolinium-based nanoparticles for MR-Imaging and Photodynamic therapy
- PET-MRI nanoparticles imaging of blood-brain barrier damage and modulation after stroke reperfusion
- Category: Archives Publications 2007
- Category: Archives Publications 2011
- Category: Archives Publications 2012
- Category: Archives Publications 2013
- Category: Archives Publications 2014
- Category: Archives Publications 2015
- Category: Archives Publications 2016
- Category: Archives Publications 2017
- Category: Archives Publications 2018
- Category: Archives Publications 2019
- Category: Archives Publications 2020
- Category: Archives Publications 2021
- Category: Archives Publications 2022
- Category: Archives Publications 2023
- Category: Events
- Category: Press Release
- Category: Press Release Major
- Category: Scientific Publications
- Category: AGuIX Characterization
- 2022 – Archives Scientific Publications: AGuIX® Characterization
- Identification of Molecular Fragments in Equilibrium with Polysiloxane Ultrasmall Nanoparticles
- Biodegradation of metal-based ultra-small nanoparticles: A combined approach using TDA-ICP-MS and CE-ICP-MS
- Quantitative biodistribution and pharmacokinetics of multimodal gadolinium-based nanoparticles for lungs using ultrashort TE MRI
- Laser-induced breakdown spectroscopy: a new approach for nanoparticle’s mapping and quantification in organ tissue
- Laser spectrometry for multi-elemental imaging of biological tissues
- The issues and tentative solutions for contrast-enhanced magnetic resonance imaging at ultra-high field strength
- Coupling of HPLC with electrospray ionization mass spectrometry for studying the aging of ultrasmall multifunctional gadolinium-based nanoparticles
- Mapping nanoparticles injected into a biological tissue using laser-induced breakdown spectroscopy
- Contrast enhanced lung MRI in mice using ultra-short echo time radial imaging and intratracheally administrated Gd-based contrast agent
- Mapping of native inorganic elements and injected nanoparticles in a biological organ with laser-induced plasma
- In vitro radiosensitizing effects of ultrasmall gadolinium based particles on tumour cells
- Three-dimensionnal quantitative MRI of aerosolized gadolinium-based nanoparticles and contrast agents in isolated ventilated porcine lungs
- Human serum albumin in the presence of AGuIX nanoagents: structure stabilization without direct interaction
- Nebulised gadolinium-based nanoparticles for a multimodal approach : quantitative and qualitative lung distribution using magnetic resonance and scintigraphy imaging in solated ventilated porcine lungs
- Taylor dispersion analysis coupled to inductively coupled plasma mass spectrometry for ultrasmall nanoparticle size measurement : from drug product to biological media studies
- Unique features of brain metastases – targeted AGuIX nanoparticles vs their constituents: a focus on glutamate-.GABA-ergic neurotransmission in cortex nerve terminals
- 2021 – Archives Scientific Publications: AGuIX® Characterization
- 2020 – Archives Scientific Publications: AGuIX® Characterization
- Multimodal AGuIX® Nanoparticles: Size Characterization by HF5 and Optimization of the Radiolabeling with Various SPECT/PET/Theranostic Tracers
- 2019 – Archives Scientific Publications: AGuIX® Characterization
- 2016 – Archives Scientific Publications: AGuIX® Characterization
- Safety evaluation and imaging properties of gadolinium based nanoparticles in nonhuman primates
- Long-Term in vivo clearance of Gadolinium-Based AGuIX (Activation and Guiding of Irradiation by X-Ray) Nanoparticles and their Biocompatibility after Systemic Injection
- 2014 – Archives Scientific Publications: AGuIX® Characterization
- 2013 – Archives Scientific Publications: AGuIX® Characterization
- 2012 – Archives Scientific Publications: AGuIX® Characterization
- Ultrasmall Rigid Platforms as multimodal probes for medical applications
- Hybrid gadolinium oxide nanoparticles: multimodal contrast agents for in vivo imaging
- 2007 – Archives Scientific Publications: AGuIX® Characterization
- Category: AGuIX Characterization - Archives
- Category: AGuIX Characterization - Major
- Category: AGuIX Clinical
- Clinical transfer of AGuIX®-based radiation treatments for locally advanced cervical cancer: MR quantification and in vitro insights in the NANOCOL clinical trial framework
- Phase I/II study testing the combination of AGuIX nanoparticles with radiochemotherapy and concomitant temozolomide in patients with newly diagnosed glioblastoma (NANO-GBM trial protocol)
- Polymeric Metal Contrast Agents for T1-Weighted Magnetic Resonance Imaging of the Brain
- Prospects of Nanoparticle-based Radioenhancement for Radiotherapy
- Nanomedicine embraces cancer radio-immunotherapy: mechanism, design, recent advances, and clinical translation
- T1 Mapping From MPRAGE Acquisitions: Application to the Measurement of the Concentration of Nanoparticles in Tumors for Theranostic Use
- Anticancer Nanotherapeutics in Clinical Trials: The Work behind Clinical Translation of Nanomedicine
- Importance of Rose Bengal Loaded with Nanoparticles for Anti-Cancer Photodynamic Therapy
- Radiation nanosensitizers in cancer therapy-From preclinical discoveries to the outcomes of early clinical trials
- Theranostic AGuIX nanoparticles as radiosensitizer: A phase I, dose-escalation study in patients with multiple brain metastases (NANO-RAD trial)
- Studies on the Exposure of Gadolinium Containing Nanoparticles with Monochromatic X-rays Drive Advances in Radiation Therapy
- Targeting brain metastases with ultrasmall theranostic nanoparticles, a first-in-human trial from an MRI perspective
- Use of nanoparticles as radiosensitizing agents in radiotherapy: State of play
- Treatment of multiple brain metastases using gadolinium nanoparticles and radiotherapy: NANO-RAD, a phase I study protocol
- Recommendations for clinical translation of nanoparticle-enhanced radiotherapy
- Category: AGuIX Clinical - Major
- Category: AGuIX Preclinical data oncology
- Targeting Glioblastoma-Associated Macrophages for Photodynamic Therapy Using AGuIX®-Design Nanoparticles
- Recent Advances in Metal-Based NanoEnhancers for Particle Therapy
- Proof of Concept of the Radiosensitizing Effect of Gadolinium Oxide Nanoparticles in Cell Spheroids and a Tumor-Implanted Murine Model of Chondrosarcoma
- Gadolinium-based ultra-small nanoparticles augment radiotherapy-induced T-cell response to synergize with checkpoint blockade immunotherapy
- AGuIX nanoparticles enhance ionizing radiation-induced ferroptosis on tumor cells by targeting the NRF2-GPX4 signaling pathway
- Nanoparticles for MRI-guided radiation therapy: a review
- An overview of the intracellular localization of high-Z nanoradiosensitizers
- Research progress on nano-sensitizers for enhancing the effects of radiotherapy
- Anti-BCMA Immuno-NanoPET Radiotracers for Improved Detection of Multiple Myeloma
- Gadolinium-Based Nanoparticles Combined With Checkpoint Blockade Amplify Radiation-Induced Abscopal Effect And Cancer Immunotherapy
- Microdosimetric Investigation and a Novel Model of Radiosensitization in the Presence of Metallic Nanoparticles
- Radiosensitization Effect of AGuIX, a Gadolinium-Based Nanoparticle, in Nonsmall Cell Lung Cancer
- Quantitative tissue pharmacokinetics and EPR effect of AGuIX® nanoparticles: a multimodal imaging study in an orthotopic glioblastoma rat model and healthy macaque
- Gadolinium-based nanoparticles as sensitizing agents to carbon ions in head and neck tumor cells
- Ultrasmall theranostic gadolinium-based nanoparticles to improve high-grade rat glioma survival
- Evaluation of the theranostic properties of gadolinium-based nanoparticles for head and neck cancer
- Key clinical beam parameters for nanoparticle-mediated radiation dose amplification
- Effect of gadolinium-based nanoparticles on nuclear DNA damage and repair in glioblastoma tumor cells
- Improving proton therapy by metal-containing nanoparticles : nanoscale insights
- Combining ultrasmall gadolinium-based nanoparticles with photon irradiation overcomes radioresistance of head and neck squamous cell carcinoma
- Nebulized gadolinium-based nanoparticles : a theranostic approach for lung tumor imaging and radiosensitization
- Orotracheal administration of contrast agents: a new protocol for brain tumor targeting
- Gadolinium nanoparticles and contrast agent as radiation sensitizers
- Evaluation of a gadolinium-based nanoparticle (AGuIX) for contrast enhanced MRI of the liver in a rat model of hepatic colorectal cancer metastases at 9.4 tesla
- 3D Spatial Distribution of Nanoparticles in Mice Brain Metastases by X-ray Phase-Contrast Tomography
- Quantifying nanotherapeutic penetration using a hydrogel-based microsystem as a new 3D in vitro platform
- Radiation dose enhancement of gadolinium-based AGuIX nanoparticles on HeLa cells
- Targeting and in vivo imaging of non-small-cell lung cancer using nebulized multimodal contrast agents
- Gadolinium-based nanoparticles to improve the hadrontherapy performances
- Advantages of gadolinium based ultrasmall nanoparticles vs molecular gadolinium chelates for radiotherapy guided by MRI for glioma treatment
- Cell localisation of gadolinium-based nanoparticles and related radiosensitizing efficacy in glioblastoma cells
- Biodistribution of ultrasmall gadolinium-based nanoparticles as theranostic agent: Application to brain tumors
- Internalization pathways into cancer cells of gadolinium-based radiosensitizing nanoparticles
- Towards an image-guided microbeam radiation therapy using gadolinium-based nanoparticles
- Rapid evaluation of novel therapeutic strategies using a 3D collagen-based tissue-like model
- 2021 – Archives Scientific Publications: AGuIX® Preclinical Data Oncology
- Terbium-Based AGuIX-Design Nanoparticle to Mediate X-ray-Induced Photodynamic Therapy
- Imaging and Characterization of Sustained Gadolinium Nanoparticle Release from Next Generation Radiotherapy Biomaterial
- Tumor-targeted pH-low insertion peptide delivery of theranostic gadolinium nanoparticles for image-guided nanoparticle-enhanced radiation therapy
- Multiscale Selectivity and in vivo Biodistribution of NRP-1 – Targeted Theranostic AGuIX Nanoparticles for PDT of Glioblastoma
- Roadmap for metal nanoparticles in radiation therapy: current status, translational challenges, and future directions
- Enhanced MRI-guided radiotherapy with gadolinium-based nanoparticles: preclinical evaluation with an MRI-linac
- Multiparametric investigation of non functionalized-AGuIX nanoparticles in 3D human airway epithelium models demonstrates preferential targeting of tumor cells
- 2020 – Archives Scientific Publications: AGuIX® Preclinical Data Oncology
- Radiobiological Implications of Nanoparticles Following Radiation Treatment
- Study of the intracellular nanoparticle-based radiosensitization mechanisms in F98 glioma cells treated with charged particle therapy through synchrotron-based infrared microspectroscopy
- Gadolinium-Based Nanoparticles Can Overcome the Radioresistance of Head and Neck Squamous Cell Carcinoma Through the Induction of Autophagy
- Empirical and Theoretical Characterization of the Diffusion Process of Different Gadolinium-Based Nanoparticles within the Brain Tissue after Ultrasound-Induced Permeabilization of the Blood-Brain Barrier
- Gadolinium-Based Nanoparticles for Theranostic MRI-Guided Radiosensitization in Hepatocellular Carcinoma
- Synchrotron-based infrared microspectroscopy study on the radiosensitization effects of Gd nanoparticles at megavoltage radiation energies
- 2019 – Archives Scientific Publications: AGuIX® Preclinical Data Oncology
- In vivo gadolinium nanoparticle quantification with SPECT/CT
- Functionalization of Gadolinium Chelates Silica Nanoparticle through Silane Chemistry for Simultaneous MRI/64Cu PET Imaging
- Nanoparticle radio-enhancement: principles, progress and application to cancer treatment
- Comparison of gadolinium nanoparticles and molecular contrast agents for radiation therapy-enhancement
- Evaluation of Novel 64Cu-Labeled Theranostic Gadolinium-Based Nanoprobes in HepG2 Tumor-Bearing Nude Mice
- 68Ga-radiolabeled AGuIX nanoparticles as dual-modality imaging agents for PET/MRI-guided radiation therapy
- 2017 – Archives Scientific Publications: AGuIX® Preclinical Data Oncology
- Heterogeneous intratumoral distribution of gadolinium nanoparticles within U87 human glioblastoma xenografts unveiled by micro-PIXE imaging
- 3D Imaging of Nanoparticle Distribution in Biological Tissue by Laser-Induced Breakdown Spectroscopy
- 2016 – Archives Scientific Publications: AGuIX® Preclinical Data Oncology
- Advanced multimodal nanoparticles delay tumor progression with clinical radiation therapy
- Gadolinium-based nanoparticles and radiation therapy for multiple brain melanoma metastases : Proof of concept before phase I trial
- The high radiosensitizing efficiency of a trace of gadolinium-based nanoparticles in the tumor
- MRI-guided clinical 6-MV radiosensitization of glioma using a unique gadolinium-based nanoparticles injection
- Study of the biochemical effects induced by X-ray irradiations in combination with gadolinium nanoparticles in F98 glioma cells: first FTIR studies at the Emira laboratory of the SESAME synchrotron
- An MRI-based classification scheme to predict passive access of 5 to 50-nm large nanoparticles to tumors
- 2015 – Archives Scientific Publications: AGuIX® Preclinical Data Oncology
- AGuIX nanoparticles as a promising platform for image-guided radiation therapy
- 2014 – Archives Scientific Publications: AGuIX® Preclinical Data Oncology
- Paramagnetic nanoparticles to track and quantify in vivo immune human therapeutic cells
- Contrast enhanced lung MRI in mice using ultra-short echo time radial imaging and intratracheally administrated Gd-DOTA-based nanoparticles
- 2013 – Archives Scientific Publications: AGuIX® Preclinical Data Oncology
- A top-down synthesis route to ultrasmall multifunctionnal Gd-based nanoparticles for theranostic applications
- 2011 – Archives Scientific Publications: AGuIX® Preclinical Data Oncology
- Category: AGuIX Preclinical data oncology - Major
- Category: AGuIX Preclinical data oncology – Archives
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- 2023 – Archives Scientific Publications: Other Products
- 2022 – Archives Scientific Publications: Other Products
- 2021 – Archives Scientific Publications: Other Products
- 2020 – Archives Scientific Publications: Other Products
- 2019 – Archives Scientific Publications: Other Products
- 2018 – Archives Scientific Publications: Other Products
- 2017 – Archives Scientific Publications: Other Products
- 2016 – Archives Scientific Publications: Other Products
- 2015 – Archives Scientific Publications: Other Products
- 2014 – Archives Scientific Publications: Other Products
- 2013 – Archives Scientific Publications: Other Products
- 2012 – Archives Scientific Publications: Other Products
- Category: Others products - Major
- Category: Others products – Archives
- Category: Publications major home
- Category: Review
- 2023 – Archives Scientific Publications: Review
- 2022 – Archives Scientific Publications: Review
- 2021 – Archives Scientific Publications: Review
- 2020 – Archives Scientific Publications: Review
- 2018 – Archives Scientific Publications: Review
- 2016 – Archives Scientific Publications: Review
- 2015 – Archives Scientific Publications : Review
- Category: Review - Archives
- Category: Review - Major
- Category: Scientific Publications - Major
- Category: AGuIX Characterization