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AGuIX® at a glance

The goal of AGuIX® is to improve the efficacy of radiotherapy of cancer
leading to a better survival and quality of life

AGuIX® concentrates a high number of gadolinium atoms (∼15) in an ultrasmall size object (∼5 nanometers)

These key structural attributes lead to a unique combination of three pharmacological properties that can be translated into clinical benefits

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The ultrasmall size of the structure allows the selective accumulation of AGuIX® in tumors after intravenous administration

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The presence of gadolinium in the structure provides contrast imaging property to AGuIX® (positive contrast agent for MRI – Magnetic Resonance Imaging)

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The high concentration of gadolinium within the structure brings the ability of AGuIX® to enhance the radio-induced damages in tumors: radiosensitizing effect

EPR effect

Ability to target

mri with contrast agent

Ability to delineate tumor

Radiosensitizing

Ability to enhance radiotherapy energy