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A New Generation of Ultrasmall Nanoparticles Inducing Sensitization to Irradiation and Copper Depletion to Overcome Radioresistant and Invasive Cancers
Pharmaceutics, 2022, 14(4), 814.
P. Rocchi, D. Brichart-Vernos, F. Lux, I. Morfin, L. David, C. Rodriguez-Lafrasse, O. Tillement

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Multiscale selectivity and in vivo biodistribution of NRP-1 targeted theranostic AGuIX nanoparticles for PDT of glioblastoma
Int. J. Nanomedicine, 2020, 15, 8739-8758.
M. Gries, N. Thomas, J. Daouk, P. Rocchi, L. Choulier, J. Jubréaux, J. Pierson, A. Reinhard, V. Jouan-Hureaux, A. Château, S. Acherar, C. Frochot, F. Lux, O. Tillement, M. Barberi-Heyob

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Tumor targeted pH low insertion peptide delivery of thernanostic gadolinium nanoparticles for image guided enhanced radiation therapy
Transl. Oncol., 2020, 13, 100839.
W. Liu, J. Deacon, H. Yan, B. Sun, Y. Liu, D. Hegan, Q. Li, D. COman, M. Parent, F. Hyder, K. Roberts, R. Nath, O. Tillement, D. Engelman, P. Glazer

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Functionalization of theranostic AGuIX® nanoparticles for PET/MRI/optical imaging
RSC Advances, 2019, 9, 24811-24815.
V. Thakare, V. –L. Tran, M. Natuzzi, E. Thomas, M. Moreau, A. Romieu, B. Collin, A. Courteau, J.-M. Vrigneaud, C. Louis, S. Roux, F. Boschetti, O. Tillement, F. Lux, F. Denat

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Antibody-targeting of ultra-small nanoparticles enhances imaging sensitivity and enables longitudinal tracking of multiple myeloma
Nanoscale, 2019, 11, 20485-20496.
A. Detappe, M. Reidy, Y. Yu, C. Mathieux, H. V. T. Nguyen, T. P. Coroller, F. Lam, P. Jarolim, P. Harvey, A. Protti, Q. De Nguyen, J. A. Johnson, Y. Crémillieux, O. Tillement, I. M. Ghobrial, P. P. Ghoroghchian

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Ultrasmall AGuIX theranostic nanoparticles for vascular-targeted interstitial photodynamic therapy of glioblastoma
Int. J. Nanomedicine, 2017, 12, 7075-7088.
E. Thomas, L. Colombeau, M. Gries, T. Peterlini, C. Mathieu, N. Thomas, C. Boura, C. Frochot, R. Vanderesse, F. Lux, M. Barberi-Heyob, O. Tillement

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Proton MR spectroscopy and diffusion MR imaging to predict tumor response to interstitial photodynamic therapy for glioblastoma
Theranostics, 2017, 7, 436-451.
M. Toussaint, S. Pinel, F. Auger, N.Durieux, M. Thomassin, E. Thomas, A. Moussaron, D. Meng, F. Plénat, M. Amouroux, T. Bastogne, C. Frochot, O. Tillement, F. Lux, M. Barberi-Heyob

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Multimodal imaging Gd-nanoparticles functioalized with Pittsburgh compound B or a nanobody for amyloid plaques targeting
Nanomedicine, 2017, 12, 1675-1687.
J. Pansieri, M. Plissonneau, N. Stransky-Heilkron, M. Dumoulin, L. Heinrich-Balard, P. Rivory, J. –F. Morfin, E. Toth, M. J. Saraiva, E. Allémann, O. Tillement, V. Forge, F. Lux, C. Marquett

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Gd-nanoparticles functionnalization with specific peptides for β-amyloid plaques targeting
Nanobiotechnology, 2016, 14, 60.
M. Plissonneau, J. Pansieri, L. Heinrich-Balard, J.-F. Morfin, N. Stransky-Heilkron, P. Rivory, P. Mowat, M. Dumoulin, R. Cohen, E. Allemann, E. Toth, M. J. Saraiva, C. Louis, O. Tillement, V. Forge, F. Lux, C. Marquette

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Chemical and in vitro characterizations of a promising bimodal AGuIX probe able to target apoptotic cells for applications in MRI and optical imaging
Contrast Media Mol. Imaging, 2016, 11, 381-395.
M. Dentamaro, F. Lux, L. Vander Elst, N. Dauguet, S. Montante, A. Moussaron, C. Burtea, R. N. Muller, O. Tillement, S. Laurent

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Multifunctionnal ultrasmall nanoplatforms for vascular-targeted interstitial photodynamic therapy of brain tumors guided by real-time MRI
Nanomedicine: NBM, 2015, 11, 657-670.
D. Bechet, F. Auger, P. Couleaud, E. Marty, L. Ravasi, N. Durieux, C. Bonnet, F. Plénat, C. Frochot, S. Mordon, O. Tillement, R. Vanderesse, F. Lux, P. Perriat, F. Guillemin, M. Barberi-Heyob

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Ultrasmall nanoplatforms as calcium-responsive contrast agents for magnetic resonance imaging
Small, 2015, 11, 4900-4909.
A. Moussaron, S. Vibhute, A. Bianchi, S. Gündüz, S. Kotb, L. Sancey, V. Motto-Ros, S. Rizzitelli, Y. Crémillieux, F. Lux, N. K. Logothetis, O. Tillement, G. Angelovski

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Ultrasmall particles for Gd-MRI and 68Ga-PET dual imaging
Contrast Media Mol. Imaging, 2015, 10, 4, 309-319
C. Truillet, P. Bouziotis, C. Tsoukalas, J. Brugière, M. Martini, L. Sancey, T. Brichart, F. Denat, F. Boschetti, U. Darbost, I. Bonnamour, D. Stellas, C. D. Anagnostopoulos, V. Koutoudilis, L. A. Moulopoulos, P. Perriat, F. Lux, O. Tillement

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Small rigid platforms functionalization with quaternary ammonium : targeting extracellular matrix of chondrosarcoma
Nanomedicine :NBM, 2014, 10, 1887-1895.
E. Miot-Noirault, A. Vidal, J. Morlieras, P. Bonazza, P. Auzeloux, S. Besse, M. M. Dauplat, C. Peyrode, F. Degoul, C. Billotey, F. Lux, F. Redini, O. Tillement, J. –M. Chezal, D. Kryza, M. Janier

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Functionnalization of small rigid platforms with cyclic RGD peptides for targeting tumors overexpressing αvβ3 integrins
Bioconjugate Chem., 2013, 24, 1584-1597.
J. Morlieras, S. Dufort, L. Sancey, C. Truillet, A. Mignot, F. Rossetti, M. Dentamaro, S. Laurent, L. Vander Elst, R. N. Muller, R. Antoine, P. Dugourd, S. Roux, P. Perriat, F. Lux, J. –L. Coll, O. Tillement

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Development of gadolinium based nanoparticles having an affinity towards melanin
Nanoscale, 2013, 5, 1603-1615.
J. Morlieras, J.-M. Chezal, E. Miot-Noirault, A. Roux, L. Heinrich-Balard, R. Cohen, S. Tarrit, C. Truillet, A. Mignot, R. Hachani, D. Kryza, R. Antoine, P. Dugourd, P. Perriat, M. Janier, L. Sancey, F. Lux, O. Tillement

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In vivo evidence of the targeting of cartilaginous tissue by pyridinium functionalized nanoparticles
Chem. Comm., 2013, 49, 3046-3048.
J. Morlieras, J. –M. Chezal, E. Miot-Noirault, A. Vidal, S. Besse, D. Kryza, C. Truillet, A. Mignot, R. Antoine, P. Dugourd, F. Redini, L. Sancey, F. Lux, P. Perriat, M. Janier, O. Tillement

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High Resolution Cellular IRM: Gadolinium and Iron Oxides Nanoparticles for in Depth Dual Cell Imaging of Engineered Tissue Constructs
ACS Nano, 2013, 7, 7500-7512.
R. Di Corato, F. Gazeau, C. Le Visage, D. Fayol, P. Levitz, F. Lux, D. Letourneur, N. Luciani, O. Tillement, C. Wilhelm

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Bifunctionnal polypyridyl-Ru(II) complex grafted onto gadolinium-based nanoparticles for MR-Imaging and Photodynamic therapy
Dalton Trans., 2013, 42, 12410-12420.
C. Truillet, F. Lux, J. Moreau, M. Four, L. Sancey, S. Chevreux, G. Boeuf, P. Perriat, C. Frochot, R. Antoine, P. Dugourd, C. Portefaix, C. Hoeffel, M. Barberi-Heyob, C. Terryn, L. Van Gullick, G. Lemercier, O. Tillement

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Real-time monitoring of phototoxicity in nanoparticles-based photodynamic therapy : a model-based approach
PLoS ONE, 2012, 7, e48617.
H. Benachour, T. Bastogne, M. Toussaint, Y. Chemli, A. Sève, C. Frochot, F. Lux, O. Tillement, R. Vanderesse, M. Barberi-Heyob

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Multifunctionnal Peptide-Conjugated Hybrid Silica Nanoparticles for Photodynamic Therapy and MRI
Theranostics, 2012, 2, 889.
H. Benachour, A. Sève, T. Bastogne, C. Frochot, R. Vanderesse, J. Jasniewski, I. Miladi, C. Billotey, O. Tillement, F. Lux, M. Barberi-Heyob

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Long distance energy transfer photosensitizers arising in hybrid nanoparticles leading to fluorescence emission and singlet oxygen luminescence quenching
Photochem. Photobiol. Sci., 2012, 11, 803-811.
A. Sève, P. Couleaud, F. Lux, O. Tillement, P. Arnoux, J.-C. André, C. Frochot

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