WIREs Nanomed Nanobiotechnol, 2014, 6, 559-573.
P. Fries, J. N. Morelli, F. Lux, et al.
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2023 – Archives Scientific Publications: Preclinical
Recent Advances in Metal-Based NanoEnhancers for Particle Therapy
Nanomaterials (Basel). 2023 Mar 10;13(6):1011. doi: 10.3390/nano13061011.
YC.Chuang, PH.Wu, YA.Shen, et al.
Polymeric Metal Contrast Agents for T1-Weighted Magnetic Resonance Imaging of the Brain
ACS Biomater Sci Eng. 2023 Mar 13;9(3):1224-1242. doi: 10.1021/acsbiomaterials.2c01386. Epub 2023 Feb 8.
D.Foster, J.Larsen
Prospects of Nanoparticle-based Radioenhancement for Radiotherapy
ChemRxiv. Mar 10. doi: 10.3929/ethz-b-000603237.
L.Gerken, M.Gerdes, M.Pruschy, et al.
Targeting Glioblastoma-Associated Macrophages for Photodynamic Therapy Using AGuIX®-Design Nanoparticles
Pharmaceutics. 2023 Mar 20;15(3):997. doi: 10.3390/pharmaceutics15030997.
L.Lerouge, M.Gries, A.Chateau, et al.
Nanomedicine embraces cancer radio-immunotherapy: mechanism, design, recent advances, and clinical translation
Chem Soc Rev. 2023 Jan 3;52(1):47-96. doi: 10.1039/d2cs00437b.
H-Li, Q-Luo, H-Zhang, et al.
Clinical transfer of AGuIX®-based radiation treatments for locally advanced cervical cancer: MR quantification and in vitro insights in the NANOCOL clinical trial framework
Nanomedicine. 2023 Apr 20;50:102676. doi: 10.1016/j.nano.2023.102676. Online ahead of print.
P.Maury, M.Mondini, C.Chargari, et al.
Tuning ultrasmall theranostic nanoparticles for MRI contrast and radiation dose amplification
Theranostics. 2023 Aug 21;13(14):4711-4729. doi: 10.7150/thno.85663. eCollection 2023.
N.Brown, P.Rocchi, L.Carmès, et al.
Toward Clinical Transfer of Tumor-Targeted Ultrasmall Inorganic Nanoparticles
Advanced therapeutics.2023 May 13;. doi: 10.1002/adtp.202300019
L.Carmès, M.Banerjee, P.Coliat, et al.
Gadolinium-Based Nanoparticles Sensitize Ovarian Peritoneal Carcinomatosis to Targeted Radionuclide Therapy
J Nucl Med. 2023 Dec 1;64(12):1956-1964. doi: 10.2967/jnumed.123.265418.
C.Diaz Garcia-Prada, L.Carmès, S.Atis, et al.
Radiation therapy-activated nanoparticle and immunotherapy: The next milestone in oncology?
Int Rev Cell Mol Biol. 2023:378:157-200. doi: 10.1016/bs.ircmb.2023.03.005. Epub 2023 Apr 21.
S.Penninckx, J.Thariat, C.Mirjolet
Biological modeling of gadolinium-based nanoparticles radio-enhancement for kilovoltage photons: a Monte Carlo study
Cancer Nanotechnology. 2023 May 2. doi: 10.1186/s12645-023-00202-w
J.Wu, X.Xu, Y.Liang, et al.
2023 – Archives Scientific Publications: Clinical
Recent Advances in Metal-Based NanoEnhancers for Particle Therapy
Nanomaterials (Basel). 2023 Mar 10;13(6):1011. doi: 10.3390/nano13061011.
YC.Chuang, PH.Wu, YA.Shen, et al.
Polymeric Metal Contrast Agents for T1-Weighted Magnetic Resonance Imaging of the Brain
ACS Biomater Sci Eng. 2023 Mar 13;9(3):1224-1242. doi: 10.1021/acsbiomaterials.2c01386. Epub 2023 Feb 8.
D.Foster, J.Larsen
Prospects of Nanoparticle-based Radioenhancement for Radiotherapy
ChemRxiv. Mar 10. doi: 10.3929/ethz-b-000603237.
L.Gerken, M.Gerdes, M.Pruschy, et al.
Nanomedicine embraces cancer radio-immunotherapy: mechanism, design, recent advances, and clinical translation
Chem Soc Rev. 2023 Jan 3;52(1):47-96. doi: 10.1039/d2cs00437b.
H-Li, Q-Luo, H-Zhang, et al.
Clinical transfer of AGuIX®-based radiation treatments for locally advanced cervical cancer: MR quantification and in vitro insights in the NANOCOL clinical trial framework
Nanomedicine. 2023 Apr 20;50:102676. doi: 10.1016/j.nano.2023.102676. Online ahead of print.
P.Maury, M.Mondini, C.Chargari, et al.
Phase I/II study testing the combination of AGuIX nanoparticles with radiochemotherapy and concomitant temozolomide in patients with newly diagnosed glioblastoma (NANO-GBM trial protocol)
BMC Cancer. 2023 Apr 15;23(1):344. doi: 10.1186/s12885-023-10829-y.
E.Thivat, M.Casile, J.Moreau, et al.
Radiation therapy-activated nanoparticle and immunotherapy: The next milestone in oncology?
Int Rev Cell Mol Biol. 2023:378:157-200. doi: 10.1016/bs.ircmb.2023.03.005. Epub 2023 Apr 21.
S.Penninckx, J.Thariat, C.Mirjolet
2023 – Archives Scientific Publications: Review
Nanomedicine embraces cancer radio-immunotherapy: mechanism, design, recent advances, and clinical translation
Chem Soc Rev. 2023 Jan 3;52(1):47-96. doi: 10.1039/d2cs00437b.
H-Li, Q-Luo, H-Zhang, et al.
H-Li, Q-Luo, H-Zhang, et al.
Recent Advances in Metal-Based NanoEnhancers for Particle Therapy
Nanomaterials (Basel). 2023 Mar 10;13(6):1011. doi: 10.3390/nano13061011.
YC.Chuang, PH.Wu, YA.Shen, et al.
YC.Chuang, PH.Wu, YA.Shen, et al.
Polymeric Metal Contrast Agents for T1-Weighted Magnetic Resonance Imaging of the Brain
ACS Biomater Sci Eng. 2023 Mar 13;9(3):1224-1242. doi: 10.1021/acsbiomaterials.2c01386. Epub 2023 Feb 8.
D.Foster, J.Larsen
D.Foster, J.Larsen
Prospects of Nanoparticle-based Radioenhancement for Radiotherapy
ChemRxiv. Mar 10. doi: 10.3929/ethz-b-000603237.
L.Gerken, M.Gerdes, M.Pruschy, et al.
L.Gerken, M.Gerdes, M.Pruschy, et al.
Radiotherapy reimagined: Integrating nanomedicines into radiotherapy clinical trials
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2023 May-Jun;15(3):e1867.doi: 10.1002/wnan.1867. Epub 2022 Oct 28.
A.DuRoss, J.Phan, A.Lazar, et al.
A.DuRoss, J.Phan, A.Lazar, et al.
Toward Clinical Transfer of Tumor-Targeted Ultrasmall Inorganic Nanoparticles
Advanced therapeutics.2023 May 13;. doi: 10.1002/adtp.202300019
L.Carmès, M.Banerjee, P.Coliat, et al.
Radiation therapy-activated nanoparticle and immunotherapy: The next milestone in oncology?
Int Rev Cell Mol Biol. 2023:378:157-200. doi: 10.1016/bs.ircmb.2023.03.005. Epub 2023 Apr 21.
S.Penninckx, J.Thariat, C.Mirjolet
2023 – Archives Scientific Publications: Other Products
Targeting Glioblastoma-Associated Macrophages for Photodynamic Therapy Using AGuIX®-Design Nanoparticles
Pharmaceutics. 2023 Mar 20;15(3):997. doi: 10.3390/pharmaceutics15030997.
L.Lerouge, M.Gries, A.Chateau, et al.
Added Value of Scintillating Element in Cerenkov-Induced Photodynamic Therapy
Pharmaceuticals. 2023 Jan 18;16(2), 143. doi: 10.3390/ph16020143.
P.Schneller, C.Collet, Q.Been, et al.
Tuning ultrasmall theranostic nanoparticles for MRI contrast and radiation dose amplification
Theranostics. 2023 Aug 21;13(14):4711-4729. doi: 10.7150/thno.85663. eCollection 2023.
N.Brown, P.Rocchi, L.Carmès, et al.
Toward Clinical Transfer of Tumor-Targeted Ultrasmall Inorganic Nanoparticles
Advanced therapeutics.2023 May 13;. doi: 10.1002/adtp.202300019
L.Carmès, M.Banerjee, P.Coliat, et al.
2014 – Archives Scientific Publications: AGuIX® Characterization
The issues and tentative solutions for contrast-enhanced magnetic resonance imaging at ultra-high field strength
WIREs Nanomed Nanobiotechnol, 2014, 6, 559-573.
P. Fries, J. N. Morelli, F. Lux, O. Tillement, G. Schneider, A. Buecker
Laser spectrometry for multi-elemental imaging of biological tissues
Sci. Rep., 2014, 4, 6065.
L. Sancey, V. Motto-Ros, B. Busser, S. Kotb, J. –M. Benoit, A. Piednoir, F. Lux, O. Tillement, G. Panczer, J. Yu
Laser-induced breakdown spectroscopy: a new approach for nanoparticle’s mapping and quantification in organ tissue
J. Vis. Exp., 2014, 88, e51353
L. Sancey, V. Motto-Ros, S. Kotb, X. Wang, F. Lux, G. Panczer, J. Yu, O. Tillement
Quantitative biodistribution and pharmacokinetics of multimodal gadolinium-based nanoparticles for lungs using ultrashort TE MRI
Magn. Reson. Mater. Phy., 2014, 27, 303-316.
A. Bianchi, S. Dufort, F. Lux, A. Courtois, O. Tillement, J.-L. Coll, Y. Crémillieux
NH TherAguix Announces Completion of Enrollment in NANO-GBM Phase Ib/II Trial for Newly Diagnosed Glioblastoma and Publication of Positive Outcomes from Phase Ib in Clinical and Translational Radiation Oncology
NH TherAguix announced the completion of enrollment in NANO-GBM phase Ib/II trial, evaluating the combination of AGuIX® nanoparticles with radiotherapy and temozolomide in the treatment of newly diagnosed glioblastoma and the publication of the positive Phase Ib outcomes and MRI-based biodistribution data from this trial in the journal Clinical and Translational Radiation Oncology.
Tuning ultrasmall theranostic nanoparticles for MRI contrast and radiation dose amplification
Theranostics. 2023 Aug 21;13(14):4711-4729. doi: 10.7150/thno.85663. eCollection 2023.
N.Brown, P.Rocchi, L.Carmès, et al.
Radiation therapy-activated nanoparticle and immunotherapy: The next milestone in oncology?
Int Rev Cell Mol Biol. 2023:378:157-200. doi: 10.1016/bs.ircmb.2023.03.005. Epub 2023 Apr 21.
S.Penninckx, J.Thariat, C.Mirjolet
GBM trial of AGuIX nanoparticles with radiotherapy and temozolomide in the treatment of newly diagnosed Glioblastoma: Phase 1b outcomes and MRI-based biodistribution
Clinical and Translational Radiation Oncology. 2024 Jul 31. doi: 10.1016/j.ctro.2024.100833.
J.Biau, X.Durando, F.Boux, et al.
A New Generation of Ultrasmall Nanoparticles Inducing Sensitization to Irradiation and Copper Depletion to Overcome Radioresistant and Invasive Cancers
Pharmaceutics, 2022, 14(4), 814.
P. Rocchi, D. Brichart-Vernos, F. Lux, et al.
Phase I/II study testing the combination of AGuIX nanoparticles with radiochemotherapy and concomitant temozolomide in patients with newly diagnosed glioblastoma (NANO-GBM trial protocol)
BMC Cancer. 2023 Apr 15;23(1):344. doi: 10.1186/s12885-023-10829-y.
E.Thivat, M.Casile, J.Moreau, et al.
E.Thivat, M.Casile, J.Moreau, et al.
Nanomedicine embraces cancer radio-immunotherapy: mechanism, design, recent advances, and clinical translation
Chem Soc Rev. 2023 Jan 3;52(1):47-96. doi: 10.1039/d2cs00437b.
H-Li, Q-Luo, H-Zhang, et al.
H-Li, Q-Luo, H-Zhang, et al.
Clinical transfer of AGuIX®-based radiation treatments for locally advanced cervical cancer: MR quantification and in vitro insights in the NANOCOL clinical trial framework
Nanomedicine. 2023 Apr 20;50:102676. doi: 10.1016/j.nano.2023.102676. Online ahead of print.
P.Maury, M.Mondini, C.Chargari, et al.
P.Maury, M.Mondini, C.Chargari, et al.
Polymeric Metal Contrast Agents for T1-Weighted Magnetic Resonance Imaging of the Brain
ACS Biomater Sci Eng. 2023 Mar 13;9(3):1224-1242. doi: 10.1021/acsbiomaterials.2c01386. Epub 2023 Feb 8.
D.Foster, J.Larsen
D.Foster, J.Larsen
NH TherAguix and Jean PERRIN Cancer Centre in Clermont-Ferrand announcement
NH TherAguix and Jean PERRIN Cancer Centre in Clermont-Ferrand
announce the completion of phase I recruitment and the entry into Phase II for the Nano-GBM phase I/II trial in glioblastoma with the two first patients included.
Gadolinium-based nanoparticles AGuIX and their combination with ionizing radiation trigger AMPK-dependent proinflammatory reprogramming of tumor-associated macrophages
Immunologie. 2024 Jan 15. doi: 10.1101/2024.01.12.575217.
Z.Muradova, D.Tannous, A.Mostefa-Kara, et al.
Empirical and Theoretical Characterization of the Diffusion Process of Different Gadolinium-Based Nanoparticles within the Brain Tissue after Ultrasound-Induced Permeabilization of the Blood-Brain Barrier
Contrast Media Mol Imaging. 2019 Dec 1;2019:6341545. doi: 10.1155/2019/6341545. eCollection 2019.
A.Conti, R.Magnin, M.Gerstenmayer, et al.
A.Conti, R.Magnin, M.Gerstenmayer, et al.
High Resolution Cellular IRM: Gadolinium and Iron Oxides Nanoparticles for in Depth Dual Cell Imaging of Engineered Tissue Constructs
ACS Nano, 2013, 7, 7500-7512.
R. Di Corato, F. Gazeau, C. Le Visage, et al.
Nanoparticle radio-enhancement: principles, progress and application to cancer treatment
Phys Med Biol. 2018 Jan 9;63(2):02TR01. doi: 10.1088/1361-6560/aa99ce.
Z.Kuncic, S.Lacombe
Z.Kuncic, S.Lacombe
Multiscale Selectivity and in vivo Biodistribution of NRP-1 – Targeted Theranostic AGuIX Nanoparticles for PDT of Glioblastoma
Int J Nanomedicine. 2020 Nov 9;15:8739-8758. doi: 10.2147/IJN.S261352. eCollection 2020.
M.Gries, N.Thomas, J.Daouk, et al.
M.Gries, N.Thomas, J.Daouk, et al.
Multimodal AGuIX® Nanoparticles: Size Characterization by HF5 and Optimization of the Radiolabeling with Various SPECT/PET/Theranostic Tracers
Int J Med Nano Res. 2019 Feb 25.doi: 10.23937/2378-3664.1410027.
S.Huclier-Markai, E.Ntsiba, E.Thomas, et al.
S.Huclier-Markai, E.Ntsiba, E.Thomas, et al.
Long distance energy transfer photosensitizers arising in hybrid nanoparticles leading to fluorescence emission and singlet oxygen luminescence quenching
Photochem. Photobiol. Sci., 2012, 11, 803-811.
A. Sève, P. Couleaud, F. Lux, et al.
Multifunctionnal Peptide-Conjugated Hybrid Silica Nanoparticles for Photodynamic Therapy and MRI
Theranostics, 2012, 2, 889.
H. Benachour, A. Sève, T. Bastogne, et al.
Gadolinium-Based Nanoparticles Can Overcome the Radioresistance of Head and Neck Squamous Cell Carcinoma Through the Induction of Autophagy
J Biomed Nanotechnol. 2020 Jan 1;16(1):111-124. doi: 10.1166/jbn.2020.2871.
S.Simonet, C.Rodriguez-Lafrasse, D.Beal,, et al.
S.Simonet, C.Rodriguez-Lafrasse, D.Beal,, et al.
NH TherAguix Announces the completion of Phase I Recruitment for the Pancreas Cohort and the entry into Phase II in the NANOSMART phase Ib/II trial.
NHT today announced the transition to the Phase II randomized part of the NANOSMART study in the cohort of patients with pancreatic tumors
Imaging and Characterization of Sustained Gadolinium Nanoparticle Release from Next Generation Radiotherapy Biomaterial
Nanomaterials (Basel). 2020 Nov 13;10(11):2249. doi: 10.3390/nano10112249.
R.Mueller, M.Moreau, S.Yasmin-Karim et al.
R.Mueller, M.Moreau, S.Yasmin-Karim et al.
Roadmap for metal nanoparticles in radiation therapy: current status, translational challenges, and future directions
Phys Med Biol. 2020 Oct 22;65(21):21RM02. doi: 10.1088/1361-6560/ab9159.
J.Schuemann, A.Bagley, R.Berbeco, et al.
J.Schuemann, A.Bagley, R.Berbeco, et al.
Gadolinium-based nanoparticles and radiation therapy for multiple brain melanoma metastases : Proof of concept before phase I trial
Theranostics, 2016, 6, 418-427.
S. Kotb, A. Detappe, F. Lux, et al.
Microdosimetric Investigation and a Novel Model of Radiosensitization in the Presence of Metallic Nanoparticles
Pharmaceutics. 2021 Dec 18;13(12):2191. doi: 10.3390/pharmaceutics13122191.
H.Yan, D.Carlson, R.Abolfath, et al.
H.Yan, D.Carlson, R.Abolfath, et al.
Mapping of native inorganic elements and injected nanoparticles in a biological organ with laser-induced plasma
Appl. Phys. Lett., 2012, 101, 223702.
V. Motto-Ros, L. Sancey, Q. L. Ma, et al.
Comparison of gadolinium nanoparticles and molecular contrast agents for radiation therapy-enhancement
Med Phys. 2017 Nov;44(11):5949-5960. doi: 10.1002/mp.12570. Epub 2017 Oct 11.
R.Delorme, F.Taupin, M.Flaender, et al.
R.Delorme, F.Taupin, M.Flaender, et al.
Paramagnetic nanoparticles to track and quantify in vivo immune human therapeutic cells
Nanoscale. 2013 Dec 7;5(23):11409-15. doi: 10.1039/c3nr34240a
C.Aspord, D.Laurin, M.FJanier, et al.
Energy Transfer between AGuIX Nanoparticles and Photofrin under Light or X-ray Excitation for PDT Applications
Pharmaceuticals. 2024 Aug 5. doi: 10.3390/ph17081033.
B.Dhaini, P.Arnoux, J.Daouk, et al.
Proof of Concept of the Radiosensitizing Effect of Gadolinium Oxide Nanoparticles in Cell Spheroids and a Tumor-Implanted Murine Model of Chondrosarcoma
Int J Nanomedicine. 2022 Dec 23;17:6655-6673. doi: 10.2147/IJN.S390056. eCollection 2022.
MT.Aloy, J.Sidi Boumedine, A.Deville, et al.
MT.Aloy, J.Sidi Boumedine, A.Deville, et al.
Gadolinium-Based Nanoparticles Combined With Checkpoint Blockade Amplify Radiation-Induced Abscopal Effect And Cancer Immunotherapy
Research Square. 2021 Dec 20; doi:10.21203/rs.3.rs-1165183/v1
H.Song , N.He, C.Xu , et al.
Contrast enhanced lung MRI in mice using ultra-short echo time radial imaging and intratracheally administrated Gd-DOTA-based nanoparticles
Magn Reson Med. 2013 Nov;70(5):1419-26.doi: 10.1002/mrm.24580. Epub 2012 Dec 11.
A.Bianchi, F.Lux, O.Tillement, et al.
A.Bianchi, F.Lux, O.Tillement, et al.
2022 – Archives Scientific Publications: Preclinical
Importance of Rose Bengal Loaded with Nanoparticles for Anti-Cancer Photodynamic Therapy
Pharmaceuticals (Basel). 2022 Aug 31;15(9):1093. doi: 10.3390/ph15091093.
B.Dhaini, L.Wagner, M.Moinard, et al.
Radiotherapy reimagined: Integrating nanomedicines into radiotherapy clinical trials
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2023 May-Jun;15(3):e1867. doi: 10.1002/wnan.1867. Epub 2022 Oct 28.
A.DuRoss, J.Phan, A.Lazar, et al.
Anticancer Nanotherapeutics in Clinical Trials: The Work behind Clinical Translation of Nanomedicine
Int J Mol Sci. 2022 Nov 2;23(21):13368. doi: 10.3390/ijms232113368.
A.Parodi, E.Kolesova, Maya.Voronina, et al.
Nanoparticles for MRI-guided radiation therapy: a review
Cancer Nano 13. 2022 Nov 12; doi: 10.1186/s12645-022-00145-8.
L.Smith, H.Byrne, D.Waddington, et al.
An overview of the intracellular localization of high-Z nanoradiosensitizers
Prog Biophys Mol Biol. 2022 Nov;175:14-30. doi: 10.1016/j.pbiomolbio.2022.08.006. Epub 2022 Aug 24.
M.Varzandeh, S.Labbaf, J.Varshosaz, et al.
Research progress on nano-sensitizers for enhancing the effects of radiotherapy
Materials Advances. 2022 Mar 25;doi: 10.1039/D2MA00094F.
Y.Zhang, X.Han, Y.Liu, et al.
Proof of Concept of the Radiosensitizing Effect of Gadolinium Oxide Nanoparticles in Cell Spheroids and a Tumor-Implanted Murine Model of Chondrosarcoma
Int J Nanomedicine. 2022 Dec 23;17:6655-6673. doi: 10.2147/IJN.S390056. eCollection 2022.
MT.Aloy, J.Sidi Boumedine, A.Deville, et al.
2024 – Archives Scientific Publications: Clinical
Nanotechnology-based delivery systems to overcome drug resistance in cancer
Medical Review. 2024 Feb 20. doi: 10.1515/mr-2023-0058
H.Patel, J.Li , L.Bo, et al.
Quantifying gadolinium-based nanoparticle uptake distributions in brain metastases via magnetic resonance imaging
Scientific Reports, 2024 May 25. Article number: 11959 (2024).
S.Bennett, C.Verry, E.Kaza, et al.
Clinical and Translational Radiation Oncology. 2024 Jul 31. doi: 10.1016/j.ctro.2024.100833.
J.Biau, X.Durando, F.Boux, et al.
2020 – Archives Scientific Publications: Preclinical
Gadolinium-Based Nanoparticles Can Overcome the Radioresistance of Head and Neck Squamous Cell Carcinoma Through the Induction of Autophagy
J Biomed Nanotechnol. 2020 Jan 1;16(1):111-124. doi: 10.1166/jbn.2020.2871.
S.Simonet, C.Rodriguez-Lafrasse, D.Beal,, et al.
Radiobiological Implications of Nanoparticles Following Radiation Treatment
Part Part Syst Charact. 2020 Apr;37(4):1900411. doi: 10.1002/ppsc.201900411. Epub 2020 Mar 3.
R.Ahmad, G.Schettino, G.Royle, et al.
Enhanced MRI-guided radiotherapy with gadolinium-based nanoparticles: preclinical evaluation with an MRI-linac
Cancer Nano 11. 2020 Oct 06; doi: 10.1186/s12645-020-00065-5.
H.L.Byrne, G.Le Duc, F.Lux, et al.
Multiscale Selectivity and in vivo Biodistribution of NRP-1 – Targeted Theranostic AGuIX Nanoparticles for PDT of Glioblastoma
Int J Nanomedicine. 2020 Nov 9;15:8739-8758. doi: 10.2147/IJN.S261352. eCollection 2020.
M.Gries, N.Thomas, J.Daouk, et al.
Tumor-targeted pH-low insertion peptide delivery of theranostic gadolinium nanoparticles for image-guided nanoparticle-enhanced radiation therapy
Transl Oncol. 2020 Nov;13(11):100839. doi: 10.1016/j.tranon.2020.100839. Epub 2020 Aug 4.
W.Liu, J.Deacon, H.Yan, et al.
Study of the intracellular nanoparticle-based radiosensitization mechanisms in F98 glioma cells treated with charged particle therapy through synchrotron-based infrared microspectroscopy
Analyst. 2020 Mar 16;145(6):2345-2356. doi: 10.1039/c9an02350j.
I.Martínez-Rovira, O.Seksek, I.Dokic , et al.
I.Martínez-Rovira, O.Seksek, I.Dokic , et al.
Imaging and Characterization of Sustained Gadolinium Nanoparticle Release from Next Generation Radiotherapy Biomaterial
Nanomaterials (Basel). 2020 Nov 13;10(11):2249. doi: 10.3390/nano10112249.
R.Mueller, M.Moreau, S.Yasmin-Karim et al.
R.Mueller, M.Moreau, S.Yasmin-Karim et al.
Roadmap for metal nanoparticles in radiation therapy: current status, translational challenges, and future directions
Phys Med Biol. 2020 Oct 22;65(21):21RM02. doi: 10.1088/1361-6560/ab9159.
J.Schuemann, A.Bagley, R.Berbeco, et al.
Recent Advances in Metal-Based NanoEnhancers for Particle Therapy
Nanomaterials (Basel). 2023 Mar 10;13(6):1011. doi: 10.3390/nano13061011.
YC.Chuang, PH.Wu, YA.Shen, et al.
YC.Chuang, PH.Wu, YA.Shen, et al.
Radiotherapy reimagined: Integrating nanomedicines into radiotherapy clinical trials
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2023 May-Jun;15(3):e1867. doi: 10.1002/wnan.1867. Epub 2022 Oct 28.
A.DuRoss, J.Phan, A.Lazar, et al.
A.DuRoss, J.Phan, A.Lazar, et al.
2022 – Archives Scientific Publications: Clinical
Importance of Rose Bengal Loaded with Nanoparticles for Anti-Cancer Photodynamic Therapy
Pharmaceuticals (Basel). 2022 Aug 31;15(9):1093. doi: 10.3390/ph15091093.
B.Dhaini, L.Wagner, M.Moinard, et al.
Radiotherapy reimagined: Integrating nanomedicines into radiotherapy clinical trials
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2023 May-Jun;15(3):e1867. doi: 10.1002/wnan.1867. Epub 2022 Oct 28.
A.DuRoss, J.Phan, A.Lazar, et al.
Anticancer Nanotherapeutics in Clinical Trials: The Work behind Clinical Translation of Nanomedicine
Int J Mol Sci. 2022 Nov 2;23(21):13368. doi: 10.3390/ijms232113368.
A.Parodi, E.Kolesova, Maya.Voronina, et al.
Added Value of Scintillating Element in Cerenkov-Induced Photodynamic Therapy
Pharmaceuticals. 2023 Jan 18;16(2), 143. doi: 10.3390/ph16020143.
P.Schneller, C.Collet, Q.Been, et al.
P.Schneller, C.Collet, Q.Been, et al.
Targeting Glioblastoma-Associated Macrophages for Photodynamic Therapy Using AGuIX®-Design Nanoparticles
Pharmaceutics. 2023 Mar 20;15(3):997. doi: 10.3390/pharmaceutics15030997.
L.Lerouge, M.Gries, A.Chateau, et al.
L.Lerouge, M.Gries, A.Chateau, et al.
Gadolinium-Based Nanoparticles Sensitize Ovarian Peritoneal Carcinomatosis to Targeted Radionuclide Therapy
J Nucl Med. 2023 Dec 1;64(12):1956-1964. doi: 10.2967/jnumed.123.265418.
C.Diaz Garcia-Prada, L.Carmès, S.Atis, et al.
Biological modeling of gadolinium-based nanoparticles radio-enhancement for kilovoltage photons: a Monte Carlo study
Cancer Nanotechnology. 2023 May 2. doi: 10.1186/s12645-023-00202-w
J.Wu, X.Xu, Y.Liang, et al.
2024 – Archives Scientific Publications : Review
Nanotechnology-based delivery systems to overcome drug resistance in cancer
Medical Review. 2024 Feb. doi: 10.1515/mr-2023-0058
H.Patel, J.Li , L.Bo, et al.
NH TherAguix announces the publication of promising preclinical results of AGuIX® in combination with targeted radioligand therapies (TRT)
NH TherAguix announcesthe publication of promising preclinical results of AGuIX® in combination with targeted radioligand therapies (TRT) in the Journal of Nuclear Medicine (October, 2023).
2020 – Archives Scientific Publications: AGuIX® Characterization
Nebulised gadolinium-based nanoparticles for a multimodal approach : quantitative and qualitative lung distribution using magnetic resonance and scintigraphy imaging in solated ventilated porcine lungs
Int. J. Nanomedicine, 2020, 15, 7251-7262.
Y. Montigaud, J. Pourchez, L. Leclerc, et al.
Human serum albumin in the presence of AGuIX nanoagents: structure stabilization without direct interaction
Int. J. Mol. Sci., 2020, 21, 4673.
X. Yang, M. Bolsa-Ferruz, L. Marichal, et al.
Three-dimensionnal quantitative MRI of aerosolized gadolinium-based nanoparticles and contrast agents in isolated ventilated porcine lungs
Magn. Reson. Med., 2020, 83, 1774-172.
Y. Crémillieux, Y. Montigaud, C. Bal, et al.
NH TherAguix announces the release of a new clinical batch for it’s drug AGuIX manufactured by CARBOGEN AMCIS
MEYLAN, France, BUBENDORF, Switzerland (November 3rd, 2021) – NH TherAguix, a clinical stage company developing innovative nanomedicine for the treatment of cancer, and CARBOGEN AMCIS, a pharmaceutical process development and Active Pharmaceutical Ingredient (API) and drug products manufacturing company, announced today the release of a new batch of AGuIX Drug Product for clinical trials.
2013 – Archives Scientific Publications: Other Products
Functionnalization of small rigid platforms with cyclic RGD peptides for targeting tumors overexpressing αvβ3 integrins
Bioconjugate Chem., 2013, 24, 1584-1597.
J. Morlieras, S. Dufort, L. Sancey, C. Truillet, A. Mignot, F. Rossetti, M. Dentamaro, S. Laurent, L. Vander Elst, R. N. Muller, R. Antoine, P. Dugourd, S. Roux, P. Perriat, F. Lux, J. –L. Coll, O. Tillement
Development of gadolinium based nanoparticles having an affinity towards melanin
Nanoscale, 2013, 5, 1603-1615.
J. Morlieras, J.-M. Chezal, E. Miot-Noirault, A. Roux, L. Heinrich-Balard, R. Cohen, S. Tarrit, C. Truillet, A. Mignot, R. Hachani, D. Kryza, R. Antoine, P. Dugourd, P. Perriat, M. Janier, L. Sancey, F. Lux, O. Tillement
In vivo evidence of the targeting of cartilaginous tissue by pyridinium functionalized nanoparticles
Chem. Comm., 2013, 49, 3046-3048.
J. Morlieras, J. –M. Chezal, E. Miot-Noirault, A. Vidal, S. Besse, D. Kryza, C. Truillet, A. Mignot, R. Antoine, P. Dugourd, F. Redini, L. Sancey, F. Lux, P. Perriat, M. Janier, O. Tillement
High Resolution Cellular IRM: Gadolinium and Iron Oxides Nanoparticles for in Depth Dual Cell Imaging of Engineered Tissue Constructs
ACS Nano, 2013, 7, 7500-7512.
R. Di Corato, F. Gazeau, C. Le Visage, D. Fayol, P. Levitz, F. Lux, D. Letourneur, N. Luciani, O. Tillement, C. Wilhelm
Bifunctionnal polypyridyl-Ru(II) complex grafted onto gadolinium-based nanoparticles for MR-Imaging and Photodynamic therapy
Dalton Trans., 2013, 42, 12410-12420.
C. Truillet, F. Lux, J. Moreau, M. Four, L. Sancey, S. Chevreux, G. Boeuf, P. Perriat, C. Frochot, R. Antoine, P. Dugourd, C. Portefaix, C. Hoeffel, M. Barberi-Heyob, C. Terryn, L. Van Gullick, G. Lemercier, O. Tillement
NH TherAguix announces continuation of the Phase II NANOBRAINMETS trial in the treatment of brain metastases after completion of a futility analysis
NH TherAguix announced that the Data Safety and Monitoring Board (DSMB) has validated the continuation of the Phase II trial, NANOBRAINMETS, managed by the Dana Farber Cancer Institute, following the futility analysis scheduled after the enrollment and follow up of 50% of patients in the study.
2018 – Archives Scientific Publications: Review
Magnetic nanoparticles applications for amyloidosis study and detection: a review
Nanomaterials, 2018, 8, 0740.
J. Pansieri, M. Gerstenmeyer, F. Lux, S. Mériaux, O. Tillement, V. Forge, B. Larrat, C. Marquette
Nanoparticle radio-enhancement: principles, progress and application to cancer treatment
Phys Med Biol. 2018 Jan 9;63(2):02TR01. doi: 10.1088/1361-6560/aa99ce.
Z.Kuncic, S.Lacombe
Z.Kuncic, S.Lacombe
Recommendations for clinical translation of nanoparticle-enhanced radiotherapy
Br J Radiol. 2018 Dec;91(1092):20180325. doi: 10.1259/bjr.20180325. Epub 2018 Sep 17.
K.Ricketts, R.Ahmad, L.Beaton, et al.
K.Ricketts, R.Ahmad, L.Beaton, et al.
2018 – Archives Scientific Publications: Other Products
A New Generation of Ultrasmall Nanoparticles Inducing Sensitization to Irradiation and Copper Depletion to Overcome Radioresistant and Invasive Cancers
Pharmaceutics, 2022, 14(4), 814.
P. Rocchi, D. Brichart-Vernos, F. Lux, I. Morfin, L. David, C. Rodriguez-Lafrasse, O. Tillement
Functionalization of Gadolinium Chelates Silica Nanoparticle through Silane Chemistry for Simultaneous MRI/64Cu PET Imaging
Contrast Media Mol Imaging. 2018 Nov 1;2018:7938267. doi: 10.1155/2018/7938267. eCollection 2018.
VL.Tran, V.Thakare, M.Natuzzi, et al.
2022 – Archives Scientific Publications: Other Products
A New Generation of Ultrasmall Nanoparticles Inducing Sensitization to Irradiation and Copper Depletion to Overcome Radioresistant and Invasive Cancers
Pharmaceutics, 2022, 14(4), 814.
P. Rocchi, D. Brichart-Vernos, F. Lux, I. Morfin, L. David, C. Rodriguez-Lafrasse, O. Tillement
Anti-BCMA Immuno-NanoPET Radiotracers for Improved Detection of Multiple Myeloma
Adv Healthc Mater. 2022 Jan;11(2):e2101565. doi: 10.1002/adhm.202101565. Epub 2021 Nov 7.
E.Thomas, C.Mathieu, P.Moreno-Gaona, et al.
Importance of Rose Bengal Loaded with Nanoparticles for Anti-Cancer Photodynamic Therapy
Pharmaceuticals (Basel). 2022 Aug 31;15(9):1093. doi: 10.3390/ph15091093.
B.Dhaini, L.Wagner, M.Moinard, et al.
2021 – Archives Scientific Publications: Preclinical
Radiation nanosensitizers in cancer therapy-From preclinical discoveries to the outcomes of early clinical trials
Bioeng Transl Med. 2021 Sep 23;7(1):e10256. doi: 10.1002/btm2.10256. eCollection 2022 Jan.
C.Bilynsky, N.Millot, AL.Papa
Terbium-Based AGuIX-Design Nanoparticle to Mediate X-ray-Induced Photodynamic Therapy
Pharmaceuticals (Basel). 2021 Apr 22;14(5):396. doi: 10.3390/ph14050396.
J.Daouk, M.Iltis, B.Dhaini, et al.
Gadolinium-Based Nanoparticles Combined With Checkpoint Blockade Amplify Radiation-Induced Abscopal Effect And Cancer Immunotherapy
Research Square. 2021 Dec 20; doi:10.21203/rs.3.rs-1165183/v1
H.Song , N.He, C.Xu , et al.
Anti-BCMA Immuno-NanoPET Radiotracers for Improved Detection of Multiple Myeloma
Adv Healthc Mater. 2022 Jan;11(2):e2101565. doi: 10.1002/adhm.202101565. Epub 2021 Nov 7.
E.Thomas, C.Mathieu, P.Moreno-Gaona, et al.
E.Thomas, C.Mathieu, P.Moreno-Gaona, et al.
Microdosimetric Investigation and a Novel Model of Radiosensitization in the Presence of Metallic Nanoparticles
Pharmaceutics. 2021 Dec 18;13(12):2191. doi: 10.3390/pharmaceutics13122191.
H.Yan, D.Carlson, R.Abolfath, et al.
2019 – Archives Scientific Publications: Other Products
Functionalization of theranostic AGuIX® nanoparticles for PET/MRI/optical imaging
RSC Advances, 2019, 9, 24811-24815.
V. Thakare, V. –L. Tran, M. Natuzzi, E. Thomas, M. Moreau, A. Romieu, B. Collin, A. Courteau, J.-M. Vrigneaud, C. Louis, S. Roux, F. Boschetti, O. Tillement, F. Lux, F. Denat
Antibody-targeting of ultra-small nanoparticles enhances imaging sensitivity and enables longitudinal tracking of multiple myeloma
Nanoscale, 2019, 11, 20485-20496.
A. Detappe, M. Reidy, Y. Yu, C. Mathieux, H. V. T. Nguyen, T. P. Coroller, F. Lam, P. Jarolim, P. Harvey, A. Protti, Q. De Nguyen, J. A. Johnson, Y. Crémillieux, O. Tillement, I. M. Ghobrial, P. P. Ghoroghchian
Multimodal AGuIX® Nanoparticles: Size Characterization by HF5 and Optimization of the Radiolabeling with Various SPECT/PET/Theranostic Tracers
Int J Med Nano Res. 2019 Feb 25.doi: 10.23937/2378-3664.1410027.
S.Huclier-Markai, E.Ntsiba, E.Thomas, et al.
2019 – Archives Scientific Publications: Preclinical
Empirical and Theoretical Characterization of the Diffusion Process of Different Gadolinium-Based Nanoparticles within the Brain Tissue after Ultrasound-Induced Permeabilization of the Blood-Brain Barrier
Contrast Media Mol Imaging. 2019 Dec 1;2019:6341545. doi: 10.1155/2019/6341545. eCollection 2019.
A.Conti, R.Magnin, M.Gerstenmayer, et al.
A.Conti, R.Magnin, M.Gerstenmayer, et al.
Gadolinium-Based Nanoparticles for Theranostic MRI-Guided Radiosensitization in Hepatocellular Carcinoma
Front Bioeng Biotechnol. 2019 Nov 27;7:368. doi: 10.3389/fbioe.2019.00368. eCollection 2019.
P.Hu, Z.Fu, G.Liu, et al.
Multimodal AGuIX® Nanoparticles: Size Characterization by HF5 and Optimization of the Radiolabeling with Various SPECT/PET/Theranostic Tracers
Int J Med Nano Res. 2019 Feb 25.doi: 10.23937/2378-3664.1410027.
S.Huclier-Markai, E.Ntsiba, E.Thomas, et al.
In vivo gadolinium nanoparticle quantification with SPECT/CT
EJNMMI Phys. 2019 Jun 18;6(1):9. doi: 10.1186/s40658-019-0246-y.
O.Kochebina, A.Halty, J.Taleb, et al.
Synchrotron-based infrared microspectroscopy study on the radiosensitization effects of Gd nanoparticles at megavoltage radiation energies
Analyst. 2019 Sep 9;144(18):5511-5520. doi: 10.1039/c9an00792j.
I.Martínez-Rovira, O.Seksek, J.Puxeu, et al.
NH TherAguix receives FDA Fast Track designationfor AGuIX®
NH TherAguix receives FDA Fast Track designation for AGuIX®, its novel radio-enhancer in the treatment of malignant gliomas, and provides an update on its developments and prospects.
2024 – Archives Scientific Publications: Preclinical
AGuIX nanoparticle-nanobody bioconjugates to target immune checkpoint receptors
Nanoscale. 2024 Feb 1;16(5):2347-2360. doi: 10.1039/d3nr04777f.
L.Carmès, G.Bort, F.Lux, et al.
Gadolinium-based nanoparticles AGuIX and their combination with ionizing radiation trigger AMPK-dependent proinflammatory reprogramming of tumor-associated macrophages
Immunologie. 2024 Jan 15. doi: 10.1101/2024.01.12.575217.
Z.Muradova, D.Tannous, A.Mostefa-Kara, et al.
2012 – Archives Scientific Publications: Preclinical
Contrast enhanced lung MRI in mice using ultra-short echo time radial imaging and intratracheally administrated Gd-DOTA-based nanoparticles
Magn Reson Med. 2013 Nov;70(5):1419-26.doi: 10.1002/mrm.24580. Epub 2012 Dec 11.
A.Bianchi, F.Lux, O.Tillement, et al.
2013 – Archives Scientific Publications: AGuIX® Characterization
Coupling of HPLC with electrospray ionization mass spectrometry for studying the aging of ultrasmall multifunctional gadolinium-based nanoparticles
Anal. Chem., 2013, 85, 10440-10447.
C. Truillet, F. Lux, O. Tillement, P. Dugourd, R. Antoine
Mapping nanoparticles injected into a biological tissue using laser-induced breakdown spectroscopy
Spectrochim. Acta B, 2013, 83, 168-174.
V. Motto-Ros, L. Sancey, X. C. Wang, Q. L. Ma, F. Lux, X. S. Bai, G. Panczer, O. Tillement, J. Yu
Contrast enhanced lung MRI in mice using ultra-short echo time radial imaging and intratracheally administrated Gd-based contrast agent
Magn. Reson. Med., 2013, 70, 1419-1426.
Bianchi, F. Lux, O. Tillement, Y. Crémillieux
2013 – Archives Scientific Publications: Preclinical
Development of gadolinium based nanoparticles having an affinity towards melanin
Nanoscale. 2013 Feb 21;5(4):1603-15. doi: 10.1039/c2nr33457g.
J.Morlieras, JM.Chezal, E.Miot-Noirault, et al.
Paramagnetic nanoparticles to track and quantify in vivo immune human therapeutic cells
Nanoscale. 2013 Dec 7;5(23):11409-15. doi: 10.1039/c3nr34240a
C.Aspord, D.Laurin, M.FJanier, et al.
2017 – Archives Scientific Publications: Other Disease
Magnetic resonance lymphography at 9.4 T using a gadolinium-based nanoparticle in rat: investigations in healthy animals and a hindlimb lymphedema model
Invest. Radiol., 2017, 52, 725-733.
A. Müller, P. Fries, B. Jelvani, F. Lux, C. E. Rübe, S. Kremp, P. Giovanoli, A. Buecker, M. D. Menger, M. W. Laschke, F. S. Frueh
2017 – Archives Scientific Publications: Preclinical
68Ga-radiolabeled AGuIX nanoparticles as dual-modality imaging agents for PET/MRI-guided radiation therapy
Nanomedicine (Lond). 2017 Jul;12(13):1561-1574. doi: 10.2217/nnm-2017-0032.
P.Bouziotis, D.Stellas, E.Thomas, et al.
Heterogeneous intratumoral distribution of gadolinium nanoparticles within U87 human glioblastoma xenografts unveiled by micro-PIXE imaging
Anal Biochem. 2017 Apr 15;523:50-57. doi: 10.1016/j.ab.2017.02.010. Epub 2017 Feb 20.
A.Carmona, S.Roudeau, B.L’Homel, et al.
Comparison of gadolinium nanoparticles and molecular contrast agents for radiation therapy-enhancement
Med Phys. 2017 Nov;44(11):5949-5960. doi: 10.1002/mp.12570. Epub 2017 Oct 11.
R.Delorme, F.Taupin, M.Flaender, et al.
Evaluation of Novel 64Cu-Labeled Theranostic Gadolinium-Based Nanoprobes in HepG2 Tumor-Bearing Nude Mice
Nanoscale Res Lett. 2017 Sep 6;12(1):523. doi: 10.1186/s11671-017-2292-5.
P.Hu, D.Cheng, T.Huang, et al.
2018 – Archives Scientific Publications: Preclinical
Nanoparticle radio-enhancement: principles, progress and application to cancer treatment
Phys Med Biol. 2018 Jan 9;63(2):02TR01. doi: 10.1088/1361-6560/aa99ce.
Z.Kuncic, S.Lacombe
Recommendations for clinical translation of nanoparticle-enhanced radiotherapy
Br J Radiol. 2018 Dec;91(1092):20180325. doi: 10.1259/bjr.20180325. Epub 2018 Sep 17.
K.Ricketts, R.Ahmad, L.Beaton, et al.
Functionalization of Gadolinium Chelates Silica Nanoparticle through Silane Chemistry for Simultaneous MRI/64Cu PET Imaging
Contrast Media Mol Imaging. 2018 Nov 1;2018:7938267. doi: 10.1155/2018/7938267. eCollection 2018.
VL.Tran, V.Thakare, M.Natuzzi, et al.
VL.Tran, V.Thakare, M.Natuzzi, et al.
2020 – Archives Scientific Publications: Other Products
Multiscale selectivity and in vivo biodistribution of NRP-1 targeted theranostic AGuIX nanoparticles for PDT of glioblastoma
Int. J. Nanomedicine, 2020, 15, 8739-8758.
M. Gries, N. Thomas, J. Daouk, P. Rocchi, L. Choulier, J. Jubréaux, J. Pierson, A. Reinhard, V. Jouan-Hureaux, A. Château, S. Acherar, C. Frochot, F. Lux, O. Tillement, M. Barberi-Heyob
Tumor targeted pH low insertion peptide delivery of thernanostic gadolinium nanoparticles for image guided enhanced radiation therapy
Transl. Oncol., 2020, 13, 100839.
W. Liu, J. Deacon, H. Yan, B. Sun, Y. Liu, D. Hegan, Q. Li, D. COman, M. Parent, F. Hyder, K. Roberts, R. Nath, O. Tillement, D. Engelman, P. Glazer
Studies on the Exposure of Gadolinium Containing Nanoparticles with Monochromatic X-rays Drive Advances in Radiation Therapy
Nanomaterials (Basel). 2020 Jul 9;10(7):1341. doi: 10.3390/nano10071341.
F.Tamanoi, K.Matsumoto, T.Le Hoang Doan, et al.
2017 – Archives Scientific Publications: Other Products
Ultrasmall AGuIX theranostic nanoparticles for vascular-targeted interstitial photodynamic therapy of glioblastoma
Int. J. Nanomedicine, 2017, 12, 7075-7088.
E. Thomas, L. Colombeau, M. Gries, T. Peterlini, C. Mathieu, N. Thomas, C. Boura, C. Frochot, R. Vanderesse, F. Lux, M. Barberi-Heyob, O. Tillement
Proton MR spectroscopy and diffusion MR imaging to predict tumor response to interstitial photodynamic therapy for glioblastoma
Theranostics, 2017, 7, 436-451.
M. Toussaint, S. Pinel, F. Auger, N.Durieux, M. Thomassin, E. Thomas, A. Moussaron, D. Meng, F. Plénat, M. Amouroux, T. Bastogne, C. Frochot, O. Tillement, F. Lux, M. Barberi-Heyob
Multimodal imaging Gd-nanoparticles functioalized with Pittsburgh compound B or a nanobody for amyloid plaques targeting
Nanomedicine, 2017, 12, 1675-1687.
J. Pansieri, M. Plissonneau, N. Stransky-Heilkron, M. Dumoulin, L. Heinrich-Balard, P. Rivory, J. –F. Morfin, E. Toth, M. J. Saraiva, E. Allémann, O. Tillement, V. Forge, F. Lux, C. Marquett
68Ga-radiolabeled AGuIX nanoparticles as dual-modality imaging agents for PET/MRI-guided radiation therapy
Nanomedicine (Lond). 2017 Jul;12(13):1561-1574. doi: 10.2217/nnm-2017-0032.
P.Bouziotis, D.Stellas, E.Thomas, et al.
Evaluation of Novel 64Cu-Labeled Theranostic Gadolinium-Based Nanoprobes in HepG2 Tumor-Bearing Nude Mice
Nanoscale Res Lett. 2017 Sep 6;12(1):523. doi: 10.1186/s11671-017-2292-5.
P.Hu, D.Cheng, T.Huang, et al.
2019 – Archives Scientific Publications: AGuIX® Characterization
Multimodal AGuIX® Nanoparticles: Size Characterization by HF5 and Optimization of the Radiolabeling with Various SPECT/PET/Theranostic Tracers
Int J Med Nano Res. 2019 Feb 25.doi: 10.23937/2378-3664.1410027.
S.Huclier-Markai, E.Ntsiba, E.Thomas, et al.
2020 – Archives Scientific Publications: Review
Roadmap for metal nanoparticles in radiation therapy: current status, translational challenges, and future directions
Phys. Med. Biol., 2020, 65, 21RM02.
J. Schuemann, A. Bagley, R. Berberco, K. Bromma, K. T. Butterworth, H. Byrne, D. B. Chithrani, S. H. Cho, J. R. Cook, V. Favaudon, Y. H. Gholami, E. Gargioni, J. F. Hainfeld, F. Heespeels, A. C. Heuskin, U. M. Ibeh, Z. Kuncic, S. Kunjachan, S. Lacombe, S. Lucas, F. Lux, S. J. McMahon, D. Nevozhay, W. Ngwa, J. D. Payne, S. Penninckx, E. Porcel, K. M. Prise, H. Rabus, S. M. Ridwan, B. Rudek, L. Sanche, B. Singh, H. M. Smilowitz, K. V. Sokolov, S. Sridhar, Y. Stanishevskiy, W. Sung, O. Tillement, N. A. Virani, W. Yantasee, S. Krishnan,
Studies on the Exposure of Gadolinium Containing Nanoparticles with Monochromatic X-rays Drive Advances in Radiation Therapy
Nanomaterials (Basel). 2020 Jul 9;10(7):1341. doi: 10.3390/nano10071341.
F.Tamanoi, K.Matsumoto, T.Le Hoang Doan, et al.
F.Tamanoi, K.Matsumoto, T.Le Hoang Doan, et al.
2020 – Archives Scientific Publications: AGuIX® Preclinical Data Oncology
Radiosensitization effect of AGuIX, a gadolinium-based nanoparticle, in nonsmall cell lung cancer
Applied Materials & Interfaces, 2020, 12, 56874-56885
Y. Du, H. Sun, F. Lux Y. Xie, L. Du, C. Xu, H. Zhang, N. He, J. Wang, Y. Liu, G. Leduc, T. Doussineau, K. Ji, Q. Wang, Z. Lin, Y. Wang, Q. Liu, O. Tillement
Enhanced MRI-guided radiotherapy with gadolinium-based nanoparticles: preclinical evaluation with an MRI-LINAC
Cancer Nanotechnology, 2020, 11, 1-14.
H. L. Byrne, G. Le Duc, F. Lux, O. Tillement, N. M. Holmes, A. James, U. Jelen, B. Dong, G. Liney, T. L. Roberts, Z. Kundic
Multiparametric investigation of non functionalized-AGuIX nanoparticles in 3D human airway epithelium models demonstrates preferential targeting of tumor cells
J. Nanobiotechnol., 2020, 18, 129.
L. Sancey, O. Sabido, Z. He, F. Rossetti, A. Guignandon, V. Bin, J. –L. Coll, M. Cottier, F. Lux, O. Tillement, S. Constant, C. Mas, D. Boudard
Gadolinium-based nanoparticles can overcome the radioresistance of head and neck squamous cell carcinoma through the induction of autophagy
J. Biomed. Nanotechnol., 2020, 16, 11-124.
S. Simonet, C. Rodriguez-Lafrasse, D. Beal, S. Gerbaud, C. Malesys, O. Tillement, F. Lux, H. Fayyad-Kazan, W. Rachidi, D. Ardail